Vizag professor develops low-cost portable early cancer detection device

Visakhapatnam: Dr Shanti Latha Pandrangi, associate professor at GITAM Deemed to be University, has developed a prototype miniaturised diagnostic platform for multi-cancer detection under the department of science and technology–supported NIDHI scheme. The project aims to make cancer diagnosis more accessible and affordable through a portable, serum-based system named CanDect Dx.The device uses six patented protein biomarkers identified through her translational research at GITAM. These biomarkers, detectable in peripheral blood serum, form the basis of a multiplex screening approach covering breast, ovarian, cervical, uterine, prostate, liver, lung, oral, and brain cancers.Unlike conventional single-analyte markers, the six-biomarker panel enables broader oncological screening. The prototype has been standardised with 350 patient samples, with validation underway on 2,000–3,000 more to refine diagnostic thresholds and improve sensitivity and specificity.Designed as an affordable alternative to CT, PET, and IHC, the device could reduce diagnostic costs, enable earlier detection, and improve clinical outcomes. Dr. Shanti Latha Pandrangi envisions integrating this platform into routine annual health screenings as a preventive diagnostic tool. "Early detection is especially critical for internal malignancies, which often present with nonspecific symptoms and are frequently diagnosed at advanced stages. Widespread screening using such technologies could shift cancer management toward earlier intervention, improving prognosis and potentially transforming cancer into a more manageable and treatable condition," said Dr. Shanti Latha.The project is being advanced through ImmuCelTek Private Limited, her biotechnology startup, which is seeking funding for large-scale validation and regulatory readiness. Recognised with GITAM's Best Researcher Award (2025), Dr. Shanti Latha has also received the EMBO fellowship and the Global Health Award from Hong Kong University. She collaborates internationally as a member of the European and American Associations for Cancer Research.